軟骨修復・軟骨再生市場 : 2028年までの世界予測

Report Overview

The global Cartilage Repair/Cartilage Regeneration Market is projected to reach USD 2.8 Billion by 2028 from USD 1.3 Billion in 2023, at a CAGR of 17.2% during the forecast period. Cell-based procedures like chondrocyte transplantation, growth factors, and stem cells are mainly driven by the, rising number of cartilage repair procedures and the increasing number of osteoarthritis cases which is expected to drive the cell-based research and advancement in a number of hospitals in upcoming years.

“The hyaline cartilage segment accounted for the highest market share in the application segment market, by application, during the forecast period.”
Based on the application of the segment, the Cartilage Repair/Cartilage Regeneration Market market is categorized into hyaline cartilage and fibrocartilage. Hyaline cartilage is expected to have the highest growth in the market, which is attributed to the availability of the funding and the rising investment in R&D and increasing growth opportunities in emerging economies will drive the hyaline cartilage market.

“The North America segment accounted for the highest market share in Cartilage Repair/Cartilage Regeneration Market Cartilage Repair/Cartilage Regeneration Market, by region, during the forecast period.”
Based on the region, the Cartilage Repair/Cartilage Regeneration Market is divided into North America, Europe, Asia Pacific, and Rest of the world. In 2022, North America had the highest market as the key players for the cartilage repair market mainly have the presence in countries like US and Canada and the growing number of knee replacement surgeries and the use of cartilage repair products for the treatment of cartilage damage or injury.

Breakdown of supply-side primary interviews by company type, designation, and region:
• By Company Type: Tier 1 (30%), Tier 2 (44%), and Tier 3 (26%)
• By Designation: C-level (30%), Director-level (33%), and Others (37%)
• By Region: North America (40%), Europe (28%), Asia-Pacific (18%),  RoW- (14%),

Prominent companies include Smith+Nephew (UK), DePuy Synthes (Johnson & Johnson) (US), Zimmer Biomet Holdings, Inc. (US), Stryker Corporation (US), Vericel Corporation (US), B. Braun Melsungen AG (US), Anika Therapeutics (US), CONMED Corporation (US), MEDIPOST (South Korea), RTI Surgical (US), Arthrex, Inc. (US), Regrow Biosciences (India), Geistlich Pharma AG (Switzerland), AlloSource (US), Orthocell Ltd, (Australia), Matricel GmbH (Germany), CartiHeal, Inc. (Israel), Regentis Biomaterials (Israel), Theracell Advanced Biotechnology (Greece) and LifeNet Health (US).

Research Coverage
This research report categorizes the Cartilage Repair/Cartilage Regeneration Market which is segmented into products used for Cartilage Repair/Cartilage Regeneration and the application and site of application.
The treatment modality for Cartilage Repair/Cartilage Regeneration is divided into two types: cell-based, i.e., chondrocyte transplantation, growth factors, and stem cells and non-cell-based, i.e., tissue scaffolds and cell-free composites. The Application segments the classised into hyaline cartilage and fibrocartilage.  The application site segment is classified as knee, hip, ankle & foot, and other application sites (nose and shoulder), and regional segment is divided into the North America, Europe, Asia Pacific and the Rest of the world. The scope of the report covers detailed information regarding the major factors like market dynamics such as drivers, restraints, challenges, and opportunities that are influencing the growth of the Cartilage Repair/Cartilage Regeneration Market.
A detailed analysis of the key industry players also the companies new launches, developments, mergers and acquisitions associated with the Cartilage Repair/Cartilage Regeneration Market has been covered. Competitive analysis of upcoming startups in the Cartilage Repair/Cartilage Regeneration Market ecosystem is covered in this report.

Key Benefits of Buying the Report:
The report will help the market leaders/new entrants in this market with information on the closest approximations of the revenue numbers for the overall Cartilage Repair/Cartilage Regeneration Market and the subsegments. This report will help stakeholders understand the competitive landscape and gain more insights to position their businesses better and plan suitable go-to-market strategies. The report also helps stakeholders understand the pulse of the market and provides them with information on key market drivers, restraints, challenges, and opportunities.

The report provides insights on the following pointers:
• Analysis of key drivers (Increasing incidence of osteoarthritis, Increasing research funding and investments and Rising number of sports and accident-related orthopedic injuries), restraints (High cost of cartilage repair surgeries and Unfavorable reimbursement scenario) opportunities (Technological advancements in the cartilage repair market and Development in the field of regenerative medicine and Challenges (Limitation of cartilage-based stem cell products and Need for skill personnel) are influencing the growth of the Cartilage Repair/Cartilage Regeneration Market.
• Product Development/Innovation: Detailed insights on upcoming technologies, research & development activities, and new product & service launches in the Cartilage Repair/Cartilage Regeneration Market.
• Market Development: Comprehensive information about lucrative markets – the report analyses the Cartilage Repair/Cartilage Regeneration Market across varied regions.
• Market Diversification: Exhaustive information about new products & services, untapped geographies, recent developments, and investments in the Cartilage Repair/Cartilage Regeneration Market.
• Competitive Assessment: In-depth assessment of market shares, growth strategies, and service offerings of leading players, among others, in the Cartilage Repair/Cartilage Regeneration Market strategies.

Table of Contents

1            INTRODUCTION            23

1.1         STUDY OBJECTIVES      23

1.2         MARKET DEFINITION   23

TABLE 1             INCLUSIONS AND EXCLUSIONS 23

1.3         MARKET SCOPE             24

1.3.1      MARKETS COVERED     24

1.3.2      YEARS CONSIDERED     24

1.3.3      CURRENCY CONSIDERED          25

1.4         STAKEHOLDERS            25

1.5         SUMMARY OF CHANGES            25

1.5.1      RECESSION IMPACT      25

2            RESEARCH METHODOLOGY     26

2.1         RESEARCH DATA           26

FIGURE 1           CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET: RESEARCH DESIGN       26

2.1.1      SECONDARY DATA       27

2.1.1.1   Secondary sources             27

2.1.2      PRIMARY DATA 28

FIGURE 2           PRIMARY SOURCES       28

2.1.2.1   Key data from primary sources         29

2.1.2.2   Key industry insights          30

2.1.2.3   Breakdown of primary interviews     30

FIGURE 3           BREAKDOWN OF PRIMARY INTERVIEWS: BY COMPANY TYPE, DESIGNATION, AND REGION    30

2.2         MARKET SIZE ESTIMATION       31

2.2.1      APPROACH 1: COMPANY REVENUE ESTIMATION APPROACH    31

FIGURE 4           BOTTOM-UP APPROACH: COMPANY REVENUE ESTIMATION              31

2.2.2      APPROACH 2: CALCULATING MARKET SIZE FROM NUMBER OF CARTILAGE REPAIR TREATMENT PROCEDURES             32

TABLE 2             REVENUE ESTIMATION APPROACH BY CALCULATING NUMBER OF CARTILAGE REPAIR TREATMENTS PROCEDURES IN US      32

2.2.3      APPROACH 3: CORPORATE PRESENTATIONS OF COMPANIES AND PRIMARY INTERVIEWS 32

2.2.4      APPROACH 4: PRIMARY INTERVIEWS    32

2.2.5      APPROACH 5: FINAL MARKET CALCULATION   33

FIGURE 5           GROWTH FORECAST    33

FIGURE 6           CAGR PROJECTIONS: SUPPLY-SIDE ANALYSIS   33

FIGURE 7           TOP-DOWN APPROACH             34

2.3         MARKET BREAKDOWN & DATA TRIANGULATION          34

FIGURE 8           DATA TRIANGULATION METHODOLOGY         35

2.4         MARKET SHARE ANALYSIS         36

2.5         MARKET ASSUMPTIONS             36

2.6         RISK ASSESSMENT         36

2.7         LIMITATIONS   37

2.8         CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET: RECESSION IMPACT ANALYSIS 37

3            EXECUTIVE SUMMARY 38

FIGURE 9           CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TREATMENT MODALITY, 2023 VS. 2028 (USD MILLION) 38

FIGURE 10         CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION, 2023 VS. 2028 (USD MILLION)     39

FIGURE 11         CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION SITE, 2023 VS. 2028 (USD MILLION)          39

FIGURE 12         CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET: GEOGRAPHIC SNAPSHOT          40

4            PREMIUM INSIGHTS      41

4.1         CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET OVERVIEW              41

FIGURE 13         INCREASING INCIDENCE OF OSTEOARTHRITIS TO DRIVE MARKET            41

4.2         NORTH AMERICA: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION AND COUNTRY, 2022           42

FIGURE 14         HYALINE CARTILAGE HELD LARGEST SHARE IN 2022    42

4.3         CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET: GEOGRAPHIC GROWTH OPPORTUNITIES         42

FIGURE 15         JAPAN TO WITNESS HIGHEST GROWTH DURING FORECAST PERIOD              42

5            MARKET OVERVIEW     43

5.1         INTRODUCTION            43

5.2         MARKET DYNAMICS     43

FIGURE 16         CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET: DRIVERS, RESTRAINTS, OPPORTUNITIES, AND CHALLENGES    43

5.2.1      MARKET DRIVERS         44

5.2.1.1   Increasing incidence of osteoarthritis             44

5.2.1.2   Increasing research funding and investments 44

5.2.1.3   Rising number of sports and accident-related orthopedic injuries             45

5.2.2      RESTRAINTS     45

5.2.2.1   High cost of cartilage repair surgeries            45

5.2.2.2   Unfavorable reimbursement scenario             45

5.2.3      OPPORTUNITIES           46

5.2.3.1   Technological advancements           46

5.2.3.2   Developments in regenerative medicine         46

5.2.4      CHALLENGES   47

5.2.4.1   Limitations of cartilage-based stem cell products         47

5.2.4.2   Need for skilled personnel 47

5.3         SUPPLY CHAIN ANALYSIS          48

FIGURE 17         DISTRIBUTION—KEY STRATEGY PREFERRED BY PROMINENT COMPANIES      48

5.4         REGULATORY LANDSCAPE       49

5.4.1      INTRODUCTION            49

5.4.2      NORTH AMERICA          49

TABLE 3             CLASSIFICATION BASED ON SUBMISSION REQUIRED FOR REGULATORY APPROVAL          49

5.4.3      EUROPE             50

5.4.4      ASIA PACIFIC    50

5.5         PATENT ANALYSIS        52

FIGURE 18         PATENT ANALYSIS FOR CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET          52

5.6         PIPELINE ANALYSIS      53

5.6.1      PIPELINE ANALYSIS, BY CLINICAL TRIAL PHASE             53

FIGURE 19         CARTILAGE REPAIR CANDIDATE PRODUCTS IN CLINICAL PHASES ONE TO FOUR 53

TABLE 4             INDICATIVE LIST OF CANDIDATES IN CLINICAL TRIALS              53

5.7         TECHNOLOGY ANALYSIS           54

6            CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TREATMENT MODALITY           55

6.1         INTRODUCTION            56

TABLE 5             CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TREATMENT MODALITY, 2021–2028 (USD MILLION)      56

6.2         CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION 56

TABLE 6             CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION) 56

TABLE 7             CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY REGION, 2021–2028 (USD MILLION)          57

TABLE 8             NORTH AMERICA: CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY COUNTRY, 2021–2028 (USD MILLION)          57

TABLE 9             EUROPE: CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY COUNTRY, 2021–2028 (USD MILLION)      57

TABLE 10           ASIA PACIFIC: CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY COUNTRY, 2021–2028 (USD MILLION)      58

6.2.1      CHONDROCYTE TRANSPLANTATION   58

6.2.1.1   Cost-effectiveness to support market growth  58

TABLE 11           CHONDROCYTE TRANSPLANTATION MARKET, BY REGION, 2021–2028 (USD MILLION)          59

TABLE 12           NORTH AMERICA: CHONDROCYTE TRANSPLANTATION MARKET, BY COUNTRY, 2021–2028 (USD MILLION)         59

6.2.2      GROWTH FACTORS      59

6.2.2.1   Promising results associated with growth factors to drive market             59

TABLE 13           GROWTH FACTORS MARKET, BY REGION, 2021–2028 (USD MILLION)          59

TABLE 14           NORTH AMERICA: GROWTH FACTORS MARKET, BY COUNTRY, 2021–2028 (USD MILLION)          60

6.2.3      STEM CELLS     60

6.2.3.1   Advancements in stem cell-based tissue engineering to support market growth              60

TABLE 15           STEM CELLS MARKET, BY REGION, 2021–2028 (USD MILLION)              60

TABLE 16           NORTH AMERICA: STEM CELLS MARKET, BY COUNTRY, 2021–2028 (USD MILLION)     61

6.3         NON-CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION              61

TABLE 17           NON-CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION) 61

TABLE 18           NON-CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY REGION, 2021–2028 (USD MILLION)          61

TABLE 19           NORTH AMERICA: NON-CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY COUNTRY, 2021–2028 (USD MILLION)          62

TABLE 20           EUROPE: NON-CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY COUNTRY, 2021–2028 (USD MILLION)      62

TABLE 21           ASIA PACIFIC: NON-CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY COUNTRY, 2021–2028 (USD MILLION)          62

6.3.1      TISSUE SCAFFOLDS      63

6.3.1.1   Benefits of one-step procedure likely to boost market growth     63

TABLE 22           TISSUE SCAFFOLDS MARKET, BY REGION, 2021–2028 (USD MILLION)          63

6.3.2      CELL-FREE COMPOSITES           63

6.3.2.1   Increasing research to support market growth 63

TABLE 23           CELL-FREE COMPOSITES MARKET, BY REGION, 2021–2028 (USD MILLION) 64

7            CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET,

BY APPLICATION SITE  65

7.1         INTRODUCTION            66

TABLE 24           CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION SITE, 2021–2028 (USD MILLION)  66

7.2         KNEE    66

7.2.1      INCREASING CASES OF KNEE ARTHROSCOPY TO DRIVE MARKET GROWTH          66

TABLE 25           KNEE CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY REGION, 2021–2028 (USD MILLION)            67

TABLE 26           NORTH AMERICA: KNEE CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY COUNTRY, 2021–2028 (USD MILLION)      67

TABLE 27           EUROPE: KNEE CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY COUNTRY, 2021–2028 (USD MILLION)      67

TABLE 28           ASIA PACIFIC: KNEE CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY COUNTRY, 2021–2028 (USD MILLION)      68

7.3         HIP       68

7.3.1      INCREASING ADOPTION OF MINIMALLY INVASIVE ARTHROSCOPY PROCEDURES TO SUPPORT MARKET GROWTH 68

TABLE 29           HIP CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY REGION, 2021–2028 (USD MILLION)            68

TABLE 30           NORTH AMERICA: HIP CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY COUNTRY, 2021–2028 (USD MILLION)      69

TABLE 31           EUROPE: HIP CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY COUNTRY, 2021–2028 (USD MILLION)      69

TABLE 32           ASIA PACIFIC: HIP CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY COUNTRY, 2021–2028 (USD MILLION)      69

7.4         ANKLE & FOOT 70

7.4.1      INCREASING SPORTS INJURIES TO DRIVE DEMAND       70

TABLE 33           ANKLE & FOOT CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY REGION, 2021–2028 (USD MILLION)          70

TABLE 34           NORTH AMERICA: ANKLE & FOOT CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY COUNTRY, 2021–2028 (USD MILLION)          70

TABLE 35           EUROPE: ANKLE & FOOT CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY COUNTRY, 2021–2028 (USD MILLION)      71

7.5         OTHER APPLICATION SITES     71

TABLE 36           CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET FOR OTHER APPLICATION SITES, BY REGION, 2021–2028 (USD MILLION)              71

TABLE 37           NORTH AMERICA: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET FOR OTHER APPLICATION SITES, BY COUNTRY, 2021–2028 (USD MILLION)          72

8            CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION  73

8.1         INTRODUCTION            74

TABLE 38           CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION, 2021–2028 (USD MILLION)           74

8.2         HYALINE CARTILAGE   74

8.2.1      HYALINE CARTILAGE SEGMENT TO HOLD LARGER MARKET SHARE              74

TABLE 39           HYALINE CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY REGION, 2021–2028 (USD MILLION)            75

TABLE 40           NORTH AMERICA: HYALINE CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY COUNTRY, 2021–2028 (USD MILLION)      75

TABLE 41           EUROPE: HYALINE CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY COUNTRY, 2021–2028 (USD MILLION)      75

TABLE 42           ASIA PACIFIC: HYALINE CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY COUNTRY, 2021–2028 (USD MILLION)      76

8.3         FIBROCARTILAGE         76

8.3.1      SUPPORT AND STRENGTH ADVANTAGES FOR SURROUNDING STRUCTURES TO DRIVE MARKET          76

TABLE 43           FIBROCARTILAGE REPAIR/REGENERATION MARKET, BY REGION, 2021–2028 (USD MILLION)       76

TABLE 44           NORTH AMERICA: FIBROCARTILAGE REPAIR/REGENERATION MARKET, BY COUNTRY, 2021–2028 (USD MILLION)         77

TABLE 45          EUROPE: FIBROCARTILAGE REPAIR/REGENERATION MARKET, BY COUNTRY, 2021–2028 (USD MILLION)            77

TABLE 46           ASIA PACIFIC: FIBROCARTILAGE REPAIR/REGENERATION MARKET, BY COUNTRY, 2021–2028 (USD MILLION)         77

9            CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY REGION             78

9.1         INTRODUCTION            79

TABLE 47           CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY REGION, 2021–2028 (USD MILLION)       79

9.2         NORTH AMERICA          79

9.2.1      NORTH AMERICA: RECESSION IMPACT 79

FIGURE 20         NORTH AMERICA: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET SNAPSHOT   80

TABLE 48           NORTH AMERICA: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY COUNTRY, 2021–2028 (USD MILLION)      81

TABLE 49           NORTH AMERICA: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TREATMENT MODALITY, 2021–2028 (USD MILLION)          81

TABLE 50           NORTH AMERICA: CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION)          81

TABLE 51           NORTH AMERICA: NON-CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION)          82

TABLE 52           NORTH AMERICA: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION, 2021–2028 (USD MILLION) 82

TABLE 53           NORTH AMERICA: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION SITE, 2021–2028 (USD MILLION)              82

9.2.2      US         83

9.2.2.1   Increasing incidence of osteoporosis to drive market    83

TABLE 54          US: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TREATMENT MODALITY, 2021–2028 (USD MILLION) 83

TABLE 55           US: CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION) 83

TABLE 56           US: NON-CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION) 84

TABLE 57          US: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION, 2021–2028 (USD MILLION)     84

TABLE 58          US: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION SITE, 2021–2028 (USD MILLION)          84

9.2.3      CANADA            85

9.2.3.1   Increasing investments in regenerative medicine research to drive market              85

TABLE 59           CANADA: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TREATMENT MODALITY, 2021–2028 (USD MILLION)           85

TABLE 60           CANADA: CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION) 85

TABLE 61           CANADA: NON-CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION) 86

TABLE 62           CANADA: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION, 2021–2028 (USD MILLION)  86

TABLE 63           CANADA: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION SITE, 2021–2028 (USD MILLION)       86

9.3         EUROPE             87

9.3.1      EUROPE: RECESSION IMPACT   87

TABLE 64           EUROPE: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY COUNTRY, 2021–2028 (USD MILLION)         87

TABLE 65           EUROPE: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TREATMENT MODALITY, 2021–2028 (USD MILLION)           88

TABLE 66           EUROPE: CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION) 88

TABLE 67           EUROPE: NON-CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION) 88

TABLE 68           EUROPE: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION, 2021–2028 (USD MILLION)  89

TABLE 69           EUROPE: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION SITE, 2021–2028 (USD MILLION)       89

9.3.2      GERMANY         89

9.3.2.1   Strong R&D base and focus on minimally invasive surgeries to support market growth   89

TABLE 70           GERMANY: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TREATMENT MODALITY, 2021–2028 (USD MILLION)           90

TABLE 71           GERMANY: CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION) 90

TABLE 72           GERMANY: NON-CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION)          90

TABLE 73           GERMANY: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION, 2021–2028 (USD MILLION)  91

TABLE 74           GERMANY: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION SITE, 2021–2028 (USD MILLION)       91

9.3.3      UK         91

9.3.3.1   Rising prevalence of joint diseases to boost demand     91

TABLE 75           UK: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TREATMENT MODALITY, 2021–2028 (USD MILLION)           92

TABLE 76           UK: CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION) 92

TABLE 77           UK: NON-CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION) 92

TABLE 78           UK: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION, 2021–2028 (USD MILLION)  93

TABLE 79           UK: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION SITE, 2021–2028 (USD MILLION)       93

9.3.4      FRANCE             93

9.3.4.1   Rising degenerative disease and healthcare expenditure to drive market   93

TABLE 80           FRANCE: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TREATMENT MODALITY, 2021–2028 (USD MILLION)           94

TABLE 81           FRANCE: CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION) 94

TABLE 82           FRANCE: NON-CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION) 94

TABLE 83           FRANCE: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION, 2021–2028 (USD MILLION)  95

TABLE 84           FRANCE: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION SITE, 2021–2028 (USD MILLION)       95

9.3.5      REST OF EUROPE           95

TABLE 85           REST OF EUROPE: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TREATMENT MODALITY, 2021–2028 (USD MILLION)          96

TABLE 86           REST OF EUROPE: CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION)          96

TABLE 87           REST OF EUROPE: NON-CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION)          96

TABLE 88           REST OF EUROPE: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION, 2021–2028 (USD MILLION) 97

TABLE 89           REST OF EUROPE: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION SITE, 2021–2028 (USD MILLION)              97

9.4         ASIA PACIFIC    97

9.4.1      ASIA PACIFIC: RECESSION IMPACT        97

FIGURE 21         ASIA PACIFIC: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET          98

TABLE 90           ASIA PACIFIC: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY COUNTRY, 2021–2028 (USD MILLION)      99

TABLE 91           ASIA PACIFIC: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TREATMENT MODALITY, 2021–2028 (USD MILLION)          99

TABLE 92           ASIA PACIFIC: CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION) 99

TABLE 93           ASIA PACIFIC: NON-CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION)          100

TABLE 94           ASIA PACIFIC: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION, 2021–2028 (USD MILLION) 100

TABLE 95           ASIA PACIFIC: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION SITE, 2021–2028 (USD MILLION)              100

9.4.2      JAPAN  101

9.4.2.1   Japan to hold largest market share throughout forecast period   101

TABLE 96           JAPAN: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TREATMENT MODALITY, 2021–2028 (USD MILLION)           101

TABLE 97           JAPAN: CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION) 101

TABLE 98           JAPAN: NON-CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION) 102

TABLE 99           JAPAN: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION, 2021–2028 (USD MILLION)  102

TABLE 100         JAPAN: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION SITE, 2021–2028 (USD MILLION)       102

9.4.3      CHINA  103

9.4.3.1   China to register highest growth in APAC market        103

TABLE 101         CHINA: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TREATMENT MODALITY, 2021–2028 (USD MILLION)           103

TABLE 102         CHINA: CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION) 103

TABLE 103         CHINA: NON-CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION) 104

TABLE 104         CHINA: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION, 2021–2028 (USD MILLION)  104

TABLE 105         CHINA: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION SITE, 2021–2028 (USD MILLION)       104

9.4.4      INDIA   105

9.4.4.1   Rising number of hospitals and developing healthcare infrastructure to propel market growth     105

TABLE 106         INDIA: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TREATMENT MODALITY, 2021–2028 (USD MILLION)           105

TABLE 107         INDIA: CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION) 105

TABLE 108         INDIA: NON-CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION) 106

TABLE 109         INDIA: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION, 2021–2028 (USD MILLION)  106

TABLE 110         INDIA: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION SITE, 2021–2028 (USD MILLION)       106

9.4.5      REST OF ASIA PACIFIC  107

TABLE 111         REST OF ASIA PACIFIC: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TREATMENT MODALITY, 2021–2028 (USD MILLION)          107

TABLE 112         REST OF ASIA PACIFIC: CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION)          107

TABLE 113         REST OF ASIA PACIFIC: NON-CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION)          108

TABLE 114         REST OF ASIA PACIFIC: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION, 2021–2028 (USD MILLION) 108

TABLE 115         REST OF ASIA PACIFIC: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION SITE, 2021–2028 (USD MILLION)              108

9.5         REST OF THE WORLD   109

9.5.1      REST OF THE WORLD: RECESSION IMPACT       109

TABLE 116         REST OF THE WORLD: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TREATMENT MODALITY, 2021–2028 (USD MILLION)          110

TABLE 117         REST OF THE WORLD: CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION)          110

TABLE 118         REST OF THE WORLD: NON-CELL-BASED CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY TYPE, 2021–2028 (USD MILLION)          110

TABLE 119         REST OF THE WORLD: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION, 2021–2028 (USD MILLION) 111

TABLE 120         REST OF THE WORLD: CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET, BY APPLICATION SITE, 2021–2028 (USD MILLION)              111

10          COMPETITIVE LANDSCAPE       112

10.1       INTRODUCTION            112

10.2       REVENUE ANALYSIS      112

FIGURE 22         TOP FIVE PLAYERS HAVE DOMINATED MARKET IN LAST FIVE YEARS  112

10.3       MARKET SHARE ANALYSIS         113

FIGURE 23         CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET: MARKET SHARE ANALYSIS, 2022             113

TABLE 121         CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET: DEGREE OF COMPETITION       113

10.4       COMPANY EVALUATION MATRIX          114

10.4.1    STARS  115

10.4.2    EMERGING LEADERS    115

10.4.3    PERVASIVE PLAYERS     115

10.4.4    PARTICIPANTS 115

FIGURE 24         GLOBAL CARTILAGE REPAIR/CARTILAGE REGENERATION MARKET: COMPANY EVALUATION MATRIX, 2022           116

10.5       COMPETITIVE SCENARIO          117

10.5.1    PRODUCT APPROVALS 117

TABLE 122         KEY PRODUCT APPROVALS, JANUARY 2020–NOVEMBER 2023              117

10.5.2    DEALS  117

TABLE 123         KEY DEALS, JANUARY 2020–NOVEMBER 2023     117

10.5.3    OTHER DEVELOPMENTS           118

TABLE 124         OTHER KEY DEVELOPMENTS, JANUARY 2020–NOVEMBER 2023              118

11          COMPANY PROFILES    119

11.1       KEY COMPANIES            119

(Business Overview, Products Offered, Recent Developments, and MnM View (Key strengths/Right to Win, Strategic Choices Made, and Weaknesses and Competitive Threats))*

11.1.1    SMITH+NEPHEW           119

TABLE 125         SMITH+NEPHEW: COMPANY OVERVIEW            119

FIGURE 25         SMITH+NEPHEW: COMPANY SNAPSHOT (2022) 120

11.1.2    DEPUY SYNTHES (JOHNSON & JOHNSON)          123

TABLE 126         JOHNSON & JOHNSON: COMPANY OVERVIEW  123

FIGURE 26         JOHNSON & JOHNSON: COMPANY SNAPSHOT (2022)    124

11.1.3    ZIMMER BIOMET HOLDINGS, INC.         127

TABLE 127         ZIMMER BIOMET HOLDINGS, INC.: COMPANY OVERVIEW              127

FIGURE 27         ZIMMER BIOMET HOLDINGS, INC.: COMPANY SNAPSHOT (2022)   128

11.1.4    STRYKER CORPORATION           131

TABLE 128         STRYKER CORPORATION: COMPANY OVERVIEW           131

FIGURE 28         STRYKER CORPORATION: COMPANY SNAPSHOT (2022)              132

11.1.5    VERICEL CORPORATION           134

TABLE 129         VERICEL CORPORATION: COMPANY OVERVIEW            134

FIGURE 29         VERICEL CORPORATION: COMPANY SNAPSHOT (2022) 134

11.1.6    B. BRAUN MELSUNGEN AG        136

TABLE 130         B. BRAUN MELSUNGEN AG: COMPANY OVERVIEW         136

FIGURE 30         B. BRAUN MELSUNGEN AG: COMPANY SNAPSHOT (2022)              137

11.1.7    ANIKA THERAPEUTICS, INC.      138

TABLE 131         ANIKA THERAPEUTICS, INC.: COMPANY OVERVIEW      138

FIGURE 31         ANIKA THERAPEUTICS, INC: COMPANY SNAPSHOT (2022)              139

11.1.8    RTI SURGICAL  140

TABLE 132         RTI SURGICAL: COMPANY OVERVIEW   140

11.1.9    CONMED CORPORATION          142

TABLE 133         CONMED CORPORATION.: COMPANY OVERVIEW          142

FIGURE 32         CONMED CORPORATION: COMPANY SNAPSHOT (2022)              143

11.1.10  ARTHREX INC.  145

TABLE 134         ARTHREX INC.: COMPANY OVERVIEW  145

11.1.11  REGROW BIOSCIENCES 146

TABLE 135         REGROW BIOSCIENCES: COMPANY OVERVIEW 146

11.1.12  MEDIPOST        147

TABLE 136         MEDIPOST: COMPANY OVERVIEW         147

FIGURE 33         MEDIPOST: COMPANY SNAPSHOT (2022)           147

11.2       OTHER PLAYERS           150

11.2.1    GEISTLICH PHARMA AG             150

11.2.2    ALLOSOURCE   150

11.2.3    ORTHOCELL LTD.         151

11.2.4    CARTIHEAL, INC.           151

11.2.5    REGENTIS BIOMATERIALS         152

11.2.6    LIFENET HEALTH          152

11.2.7    MATRICEL GMBH          153

11.2.8    THERACELL ADVANCED BIOTECHNOLOGY      153

*Details on Business Overview, Products Offered, Recent Developments, and MnM View (Key strengths/Right to Win, Strategic Choices Made, and Weaknesses and Competitive Threats) might not be captured in case of unlisted companies.

12          APPENDIX         154

12.1       DISCUSSION GUIDE      154

12.2       KNOWLEDGESTORE: MARKETSANDMARKETS’ SUBSCRIPTION PORTAL             157

12.3       CUSTOMIZATION OPTIONS      159

12.4       RELATED REPORTS       159

12.5       AUTHOR DETAILS         160